Domenico Gattilusio, Lord of Lesbos (died 1458) was the fifth ruler of an independent Lesbos from 1455 to 1458.
He was a son of Dorino of Lesbos and Orietta Doria. He succeeded his father and reigned in the island for three years.
He married Maria Giustiniani-Longo. They had no known children.
He was deposed by his younger brother Niccolò of Lesbos. His brother had him imprisoned and ordered his execution by the garrote.
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Domenico Gattilusio
Born: ? Died: 1458 |
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| Royal titles | ||
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| Preceded by Dorino |
Lord of Lesbos 1455–1458 |
Succeeded by Niccolo |